This list was compiled with the help of Ahmet Hoke, Md, PhD, Director, Neuromuscular Division, Johns Hopkins Medical Institutions. Last updated March 2008.
The following diseases are known to be autoimmune in nature:
Acute disseminated encephalomyelitis (ADEM)
Acute hemorrhagic leukoencephalitis (Hurst’s disease)
Agammaglobulinemia
Alopecia areata
Ankylosing spondylitisis
Anti-GBM/Anti-TBM disease
Antiphospholipid syndrome (APS)
Autoimmune Addison’s disease
Autoimmune aplastic anemia
Autoimmune dysautonomia
Autoimmune hepatitis
Autoimmune hemolytic anemia
Autoimmune hyperlipidemia
Autoimmune inner ear disease (AIED)
Autoimmune interstitial cystitis
Autoimmune Lymphoproliferative Syndrome (ALPS)
Autoimmune myocarditis
Autoimmune progesterone dermatitis
Autoimmune thrombocytopenic purpura (ATP)
Autoimmune thyroiditis
Balo disease
Behcet’s disease
Bullous pemphigoid
Celiac disease — sprue
Chronic inflammatory demyelinating polyneuropathy (CIDP)
Churg-Strauss syndrome
Cicatricial pemphigoid
Crohn’s disease
Cogan’s syndrome
Cold agglutinin disease
CREST disease
Dermatomyositis
Devic disease (Neuromyelitis Optica)
Diabetes Type I
Discoid lupus
Dressler’s syndrome
Eosinophilic fasciitis
Essential mixed cryoglobulinemia
Evan’s syndrome
Glomerulonephritis
Goodpasture’s syndrome
Graves’ disease
Guillain-Barre syndrome
Hashimoto’s thyroiditis
Henoch-Schonlein Purpura
IgA nephropathy
Juvenile arthritis
Lambert-Eaton myasthenic syndrome
Lichen planus
Linear IgA disease (LAD)
Lupus Nephritis
Meniere’s disease
Microscopic polyangiitis
Mixed connective tissue disease (MCTD)
Multiple Sclerosis
Myasthenia gravis
Ocular cicatricial pemphigoid
Palindromic rheumatism
Paraneoplastic cerebellar degeneration
Paroxysmal nocturnal hemoglobinuria (PNH)
Parsonnage-Turner syndrome
Pemphigus vulgaris
Pernicious anemia
Polyarteritis nodosa
Type I, II & III autoimmune polyglandular syndromes
Polymyalgia rheumatica
Polymyositis
Primary Agammaglobulinemia
Primary biliary cirrhosis
Psoriasis
Psoriatic arthritis
Idiopathic pulmonary fibrosis
POEMS syndrome
Pure red cell aplasia
Raynaud’s phenomenon
Reiter’s syndrome
Relapsing polychondritis
Rheumatic fever
Rheumatoid arthritis
Sarcoidosis
Schmidt syndrome (autoimmune polyendocrine syndrome)
Scleritis
Scleroderma
Sjogren’s syndrome
Systemic lupus erythematosus (SLE)
Testicular autoimmunity
Transverse myelitis
Ulcerative Colitis
Undifferentiated connective tissue disease (UCTD)
Uveitis
Vasculitis
Vitiglio
Wegener’s granulomatosis
The following disorders have a suspected autoimmune component
Arteriosclerosis (in some cases)
Autism
Castleman disease
Chagas’ disease
Chronic fatigue syndrome
Erythema nodosum
Fibrosing alveolitis
Herpes gestationis
Hypogammaglobulinemia
Kawasaki syndrome
Leukocytoclastic vasculitis
Lichen sclerosus
Ligeneous conjunctivitis
Lyme’s disease
Mooren’s ulcer
Mucha-Habermann disease
Narcolepsy
Pars planitis (peripheral uveitis)
Postmyocardial infarction syndrome
Postpericardiotomy sndrome
Progesterone dermatitis
Pyoderma gangrenosum
Reflex sympathetic dystrophy
Restless leg syndrome
Stiff person syndrome (in some cases)
Subacute bacterial endocarditis (SBE)
Sympathetic ophthalmia
Takayasu’s arteritis
Temporal arteritis/Giant cell arteritis
Tolosa-Hunt syndrome
The following allergic disorders involve a hypersensitive reaction of the immune system against the body itself.
Allergic asthma
Allergic eczema
Allergic rhinitis
Food allergies