How We Handle the Wear and Tear of Today’s Stress Predicts Whether We’ll Be Depressed Ten Years From Now

The way we manage our emotional responses to the stresses we meet in day-to-day life  — to what is happening right now, right here, in our life — predicts whether we’ll suffer from depression and anxiety ten years from now, says a new study in today’s Psychological Science. Researchers examined the relationship between how we handle daily stress and our mental well-being ten years later. They found that our longterm emotional health has less to do with what happens to us than with how we react to what happens to us. The better we are at managing our emotional responses and thoughts today — to whatever problem we’re facing at work or at home or with our kids — the better mental health we’ll enjoy ten years from today. The better brain we’ll own. When we respond with a lot of negativity and reactivity to our day-to-day stressors we’re more likely to be clinically depressed ten years later and experience feelings of “worthlessness, hopelessness, nervousness and anxiety.” We take those negative emotions with us, wherever we go. These findings, based on a study of 711 men and women between 25 and 74, show that mental health outcomes aren’t only affected by major life events — they are also affected by the “chronic nature of our negative emotions in response to daily stressors.” We know there are so many ways to manage our thoughts and get off the distress highway — and stay on the path. Mindfulness, lovingkindness meditation, noting our moment to moment habits of mind, breath work, yoga, seeking out acupuncture. In The Last Best Cure I spent an entire year learning from the best experts on the planet how to redirect my thoughts, calm my mind and quiet my stress response. And every day I continue to learn. Reading studies like these helps me to re-commit to these practices everyday. Because that’s what it takes. It’s not instant. It takes work. Discipline. But it’s also fun. It’s a relief to step away from our daily wear-and-tear stress-reactions and ruminations. A half-hour spent mindfully breathing or in walking meditation or yoga sure beats a half hour spent ruminating and rehashing the should haves and what ifs that are worrying me today, and it will pay off long into my future. Don’t we owe ourselves that small but priceless investment in who we are, and in who we hope to become?

Babies Get It, Grade Schoolers Get It, So Why is it So Hard For Us?

Several studies over the past few years have found that kids as young as 18 months old possess deep feelings of compassion. One study found that when toddlers show kindness to others, it’s motivated by innate feelings of compassion — not just a desire to please the adults in their lives. In the study, when toddlers saw someone in need of help their pupil sizes increased — a sign of empathic concern. After toddlers did something nice for that person, their pupils got smaller. Researchers say this means their kindness came from deep, genuine concern. In fact, toddlers showed greater signs of happiness when they gave away a special treat, than they did when they received one. Performing truly altruistic acts—acts that involve some measure of personal sacrifice—made the kids happier than helping others at no cost to themselves. This is the first study to show that altruism is intrinsic to who we are, and is rewarding even to very young kids, and that it makes them happier to give than to receive. When a behavior is intrinsically rewarding like this, especially at the earliest stages of life, it suggests to scientists that it has deep evolutionary roots. Other studies on compassion and kindness show that kids prefer other kids who are kind and, contrary to popular belief, being kind can even help kids boost their “popularity standing.” Researchers asked 400 students between the ages of 9 and 11 to perform three acts of kindness — or choose other easier tasks — over four weeks. Afterwards the kids who showed kindness saw a much greater spike in their popularity, gaining twice as many friends as their counterparts. And they also had more positive feelings about themselves. Kids said they did simple things like gave their mom a hug when she seemed stressed (always a welcome gesture at my house!), or shared their lunch with someone at school. But clearly, as we grow up and come of age, and especially when life gets more stressful, or life is hard, our innate sense of compassion goes underground. We compete at work. Drivers gesture angrily on the freeway, and turning on the news shows us that too many politicians and sports heroes choose to treat themselves well rather than others kindly, and that too many young people die in personal or gang violence, or spree shootings. It can seem there is too little kindness to spare. We face so much stress in our own day-to-day lives and see such callousness around us that we can become a little numb. And yet, even so, that innate compassion that we had at 2 or 9 or 11 is there, ready to bubble up, if we just call it up. And even those who’ve faced the hardest of lives can call it up. Researchers introduced a type of brain-changing practice known as compassion meditation — sending kind wishes to themselves, those they love and those they find problematic in their lives — to teenagers living in a foster care group in Florida. These were kids who faced a lot of day-to-day stress and adversity. Their lives were tougher than most of us can imagine. The foster teens underwent an eight-week loving kindness meditation class, keeping journals on how much they practiced.  Researchers measured their stress responses both before and after.  They also asked the teens to wear an electronically activated recorder that picks up the ambient sounds in a person’s environment – including disagreements, harsh words, altercations. And here’s what happened: the more troubled teens practiced loving kindness meditation on their own – about four or five times a week  – the more compassionate they became in their day-to-day interactions and the less altercations ensued.  Not surprisingly, teens’ stress hormone levels and inflammatory markers also went down, which we know is critical to improving physical health. Troubled foster teens, living calmer, healthier lives, simply by letting their innate compassion emerge from within for a few minutes a day. Similar work is going on in high security prisons where, after meditation classes using both compassion and breath as a focus, violence has gone down by twenty percent or more. Things haven’t changed that much from when we were 2 and 9. We feel better about ourselves when we extend kindness. Others feel better about being with us. We feel less stressed. Life is sweeter all around, for our brains, bodies and cells. I’ve found that it’s a decisive act to be compassionate — we have to choose compassion in our rush, rush lives. But learning to choose it — along with practicing the other techniques I test drove in my one year experiment to find The Last Best Cure — is a life-changing gift not only to others, but to ourselves.

Countdown Reason # 6: What Stress Does to the Gut, and What the Stressed Gut Does to the Brain

Two new studies tell us an interesting story about stress, the gut and the brain. We have a LOT of organisms in the gut. Cell for cell, we’re largely made up of bacteria. In fact, single-celled organisms, mostly bacteria, outnumber our own cells 10 to 1. Most of these live in our gut. Any alteration of the composition of good versus bad microorganisms in the gut —collectively known as our “microbiome”—impacts the state of our brain, making us more prone to anxiety, depression and low mood. And that lowered mood makes us more prone to feeling stressed out and reactive… which in turn further changes the composition of microorganisms in the gut… See the cycle? The first study appears in the journal Brain, Behavior, and Immunity. Researchers report that when we are under stress, the bacterial communities in our intestine become less diverse, allowing greater numbers of harmful bacteria to take over and party hearty. (We’ve pretty much known this for a while, after all, disorders of the gut such as irritable bowel and inflammatory bowel diseases are known to worsen during times of stress. But now we have the science to back up that clinical observation.) And that leads to the second study I wanted to talk about. It turns out that when bad bacteria are partying in our gut, it not only lowers our overall immunity, it lowers our overall mood. A sophisticated neural network transmits messages from those trillions of bacteria to our brain, exerting a powerful influence on our state of mind. That’s why scientists have begun to refer to our gut as “the second brain.” The idea that bacteria teeming in the gut can affect the mind “has just catapulted onto the scene,” say study authors. Our gut bacteria manufacture about 95 percent of our body’s supply of serotonin, which significantly influences our mood. In just the last few years evidence has piled up that the gut microbiome heavily influences our neural development, brain chemistry, emotional behavior, pain perception, learning, memory, and how our stress system is prepared to respond to life’s ups and downs. The more bad bacteria in our gut, the more anxious and moody and stressed out we feel. The more stressed out we feel the more we tip the microbial balance in the gut allowing more bad bacteria to thrive. Gastroenterologist Emeran Mayer, MD, director of the Center for Neurobiology of Stress at the University of California, Los Angeles, says that given the gut’s multifaceted ability to communicate with the brain “it’s almost unthinkable that the gut is not playing a critical role in mind states.” THE LAST BEST CURE is a toolbox to  intervene in that stress feedback cycle and help rescue both the brain in our gut and the brain in our head. — “Exposure to a social stressor alters the structure of the intestinal microbiota: Implications for stressor-induced immunomodulation” by Michael T. Bailey, Scot E. Dowd, Jeffrey D. Galley, Amy R. Hufnagle, Rebecca G. Allen and Mark Lytee; and the brief commentary on it is “The gut microbiota: A new player in the innate immune stress response?” by Monika Fleshner. The article appears in Brain, Behavior, and Immunity, Volume 25, Number 3 (March 2011), published by Elsevier.

Countdown Reason # 7: Life Channel or Pain Channel?

Research tells us that although 70 % of our day is relatively good, 28 % of it neutral, and only about 2 % of what happens to us is actually bad, we think about that negative 2 % almost all the time; it’s what we ruminate over as we shower, drive, and fall asleep.[i] It reminds me of that old saying that we wear 2 % of our wardrobe 90 % of the time. We button ourselves up in our misery cloak a lot. I think of it this way. For most of us, two different sound tracks are playing simultaneously in our mind. I call them The Life Channel and The Pain Channel. It just depends which one we tune into — and turn up. The Life Channel is the channel on which uplifting and joyful moments play. It’s the feeling I get when I am braiding my daughter’s hair. Watching my family doubled over laughing at a bad joke at the dinner table. Holding hands with my husband, or my daughter (if she lets me) as we cross a parking lot. The feeling I get when I am staring at the snow covered trees as the sun transforms their icy branches into twinkling silver lights. Or when I am meditating, clearing the mind, focusing on nothing but my breath, and I manage (now and then) to reach that sweet spot of inner quiet, inner smiling. The aha of being half way through a yoga class, and realizing I’m in a peaceful place of well-being as I focus on every muscle and breath that goes into my downward facing dog. The joy of looking into one of my best friend’s eyes and feeling the inner love that’s exchanged in our haven’t-seen-you-in-far-too-long glance, in just an ordinary instant. The Pain Channel is where we live, however, most of the time. It blares our anger, resentment, fear. Our ruminations over what happened, how it shouldn’t have, what should be happening instead. Our self-doubt. Our regret and recrimination. Our physical pain and fear over any health issues we’re facing. Sometimes we have to be on The Pain Channel; it’s what wakes us up to deal with difficult situations, make change, take action. But we don’t need to be listening to The Pain Channel 90% of the time. We just don’t. We know The Pain Channel doesn’t feel good. We just don’t know how to shut it off. It’s powerful and seductive to get wrapped up in what’s playing on The Pain Channel, especially when we are feeling at our most vulnerable. We have to have the tools to reach out and turn The Pain Channel off — and turn The Life Channel on. THE LAST BEST CURE is about having a high-speed connection to dial up to The Life Channel, especially in those moments when we need it most. So we have a real chance at living life on the right track. [i] it’s what we ruminate over as we shower, drive, and fall asleep: Rick Hanson, Ph.D., and Richard Mendius, MD. Buddha’s Brain: the Practical Neuroscience of Happiness, Love and Wisdom. New Harbinger Publications, Oakland, CA, 2009.  To see a fascinating talk given by Hanson at Google in June 2010 see http://www.youtube.com/watch?v=0EM45CpeQb4.    

Countdown Reason # 8: How Did We Miss This Chronic Disease Epidemic?

How did we miss the chronic disease epidemic now facing America? And why are we so behind in meeting the needs of the 1 out of 2 adult Americans who suffer from them? I wanted to find out the answer to that question. So I reached out to Laurie Edwards, author of the upcoming book In the Kingdom of the Sick: A Social History of Chronic Illness in America (due out in April). Laurie teaches writing for the health sciences at Northeastern University. She blogs about chronic illness, health care, and writing at A Chronic Dose. I asked Laurie, “What has caused us to be so late out of the gate in meeting needs of patients with chronic illness, and in utilizing the new brain body science? Here is what Laurie had to say: “By and large, patients with chronic illness still navigate a medical system dominated by the biomedical model of disease, where patients are diagnosed, treated, and dismissed. This strategy is only effective with acute illness; after all, chronic conditions are treatable, but not curable. While many examples of a growing shift from this model exist—more centers with integrative care, or technology that allows patients and doctors to better collaborate in care, to name just a few—much work remains. Another reason we’re slower to meet the needs of those living with chronic illness is that we get hung up on a limited view of prevention – the idea of preventing illness. For many patients who face chronic conditions, prevention is more about slowing down disease progression. We need to be realistic about what the chronically ill population looks like. It is tempting to focus more exclusively on conditions like heart disease, diabetes, and lung disease when we think about chronic illness; after all, the seven most common chronic diseases are estimated to cost a staggering $1 trillion annually.  But this is an incomplete picture. Some 50 million Americans live with autoimmune disease, and a disproportionate number of these patients are women. An estimated twenty-five percent of the population lives with chronic pain and again, women suffer in higher numbers than men.  So many chronic conditions are “invisible illnesses”  – and this invisibility shrouds the physical realities that millions of people live with daily. The gender gap also plays an important role in why chronic disease has been underacknowledged. Research shows female patients’ reports of pain are taken less seriously, treated less aggressively, and they are more likely to be characterized as emotional or psychogenic. Sex-based research into pain is one step. Already, emerging research suggests differences in the ways men and women perceive pain. Chronic illness is incredibly complex, and these complexities feed into the delay in utilizing new brain-body science.  As you write in THE LAST BEST CURE, for so many patients, Western medicine has done all it can. Patients live with ongoing symptoms, try all sorts of lifestyle interventions and alternative therapies, and wonder if this is as good as it will get. While many recognize a fundamental mind-body connection, the idea that the brain itself could hold the key to healing is an enormous paradigm shift. Hopefully, science can give us more answers, and increased collaboration between patients and provides can help us put those answers into practice.” I thank Laurie for her response to my question. I think it’s spot on. We’re late to address the skyrocketing problem of chronic illness in America, for all the reasons she cites. We have much to do. I hope that THE LAST BEST CURE helps us to better understand the emerging scientific answers and to put those answers into practice.

Countdown Reason # 9: It Doesn’t Have to Be This Way

Today I was listening to NPR as I was driving. The discussion centered on new approaches to addiction — and the fact that addiction is now being classified as a “chronic brain disease.” Experts said that 22 million American’s suffer from it. (Add this to the 133 million Americans suffering from a range of other chronic diseases and the tally rises to 155 million Americans facing chronic health issues.) And guess what one of the successful new treatment strategies for this newly labeled “chronic brain disease” turns out to be? What do practitioners who treat patients with addiction feel is critical for patients if they hope to return to a state of well-being? “Manage their thoughts,” said both experts being interviewed. The phrase kept coming up: “Managing your thoughts plays a role in recovery.” Manage the negative Floating Brain.  Monkey Brain. The constant chatter of worry, the laser focus on what’s wrong with whatever is happening, or wishing for something else to be happening. Nursing anger, frustration, fear, anxiety, resentment, regret. Ruminating. Getting caught in those states of mind that are linked to setting forth a toxic cocktail of inflammatory hormones and chemicals from brain to body to cell. During the NPR show there was a pause for a commercial for an upcoming discussion about another rising health condition, the “disturbing rising rates of heart problems in young people.” We know that heart conditions are related to chronic and acute stress. Listening to this I thought we just have to find a way out of this American Stress Crisis and what it’s costing us. We just have to. In my year-long journey to find a way out, to find THE LAST BEST CURE, I test drove everything I thought might help the 155 million Americans who have chronic conditions. Everything that scientists know activates the healing responses of the brain. So that we can walk away from Monkey Brain, and live with a newfound sense of well-being. I also wanted to help the 145 million who don‘t face chronic health worries — and who don’t want to. I put every skill I possess as an investigative science journalist to use in the process. And when I listen to the radio for twenty minutes in the car and hear about the range of pain we face, whether from this emotional struggle or that health challenge, I find myself feeling, very deeply in my heart, how much I want to be part of the change. I hope THE LAST BEST CURE can help pave the way for change. Because it just doesn’t have to be this way.  

Countdown Reason # 10: Turtle Wushu, Anyone?

A week ago I wrote this at the end of a blog on joy, memories and the brain (see Countdown Reason # 19: Why Emotional Memories of Joy Matter so Much): “I’m going to think of how to make a joy memory today. I’ll let you know how that works out on an icy, windy Friday evening in a house with with two tired working parents at the end of the week and two teenagers.” I promised I would let you know how that went. Confession. It didn’t happen that Friday night. We unexpectedly had a house full of 14-year-old girls (who happen to be naturals at making joy happen). And then the week flew by in a blur of activities, work, events, homework, doctor’s appointments, and all that jazz. But this evening things were comparatively quiet and I asked my daughter if she’d help me get “the guys” (her dad and brother) to join us in a game of Turtle Wushu. We’d come across a video of it online and when we watched it we couldn’t stop laughing. Laughter is really great for our cells, and laughter is joyful. And a joyful state of mind activates what scientists call the “positive floating brain;” those juicy good chemicals that set out from the brain and travel through our organs and cells, helping to protect us from inflammation. Moreover, it protects us from the “negative floating brain,” that state of Monkey Mind — where our inner chatter raps on about what’s going wrong, what we have to get done, what we’re angry or frustrated about, the things we’re afraid of — causing our brain to send forth a constant slow drip of inflammatory hormones and chemicals. Okay, here is the video (short at 1:42) on how to play: Turtle Wushu. (We used small crackers instead of plastic turtles. It was even more fun because the dogs “played” too in hopes of getting the spoils.) If you have teenagers it can be hard to find a game that everyone wants to play, but we were “all in” at our house for Turtle Wushu. A half hour of chasing, turning, sly maneuvers around the kitchen island, sock sliding across the floor and whirling around the breakfast table, and we were laughing pretty hard. Later, I caught my son and husband playing “Wushu” in the kitchen, just the two of them, laughing. I got “Wushu-ed” a LOT (aka I kept losing!) so the dogs really stuck by my heels in hopes of getting those flying crackers. But I got something better — a silly and wild half hour with my family, away from homework, dishes, laundry, tomorrow’s to-do list, taxes (argh), and Monkey Brain. And that felt like winning.

Countdown Reason # 12: The Number of Kids with Chronic Conditions is Skyrocketing

I’ve written about how chronic pain is on the rise, as are rates of chronic disorders. But two new studies extend our knowledge about the prevalence of chronic conditions among Americans into an area that’s quite troubling: America’s children. One study, published in the journal PAIN found that “recurrent chronic pain is overwhelmingly prevalent in children and adolescents, with, 11% to 38% of kids reporting pain.” Study authors looked at headache, back pain, abdominal pain, muscle pain and generalized pain. Rates depended on the sort of pain being reported. For instance one in four youth reported having regular headaches. Girls generally experience more pain than boys. Which is not surprising since women suffer from more chronic conditions than men in adulthood. What is most concerning, say investigators, is this: “… prevalence rates of childhood pain have increased over the last several decades.” Stress is most certainly playing a role. The second study, published in the journal Archives of Pediatric and Adolescent Medicine found that children and teen’s chronic pain is associated with that of their parents. The more chronic pain parents experienced — especially mothers — the more their children reported chronic pain: “…clear associations were observed between maternal pain and pain in adolescents and young adults…” As adults, we need to look at managing our own sense of joy and well-being not just in terms of our own health, but that of our children. Every step we take to move past “stressed-out living” and reclaim joy in our life not only enriches us, it allows our kids to see how that’s possible. And that legacy is priceless. —– Sara King, Christine T. Chambers, Anna Huguet, Rebecca C. MacNevin, Patrick J. McGrath, Louise Parker, Amanda J. MacDonald. The epidemiology of chronic pain in children and adolescents revisited: A systematic review. PAIN, 2011; 152 (12): 2729 DOI: 10.1016/j.pain.2011.07.016 (Arch Pediatr Adolesc Med. Published online November 19, 2012. doi:10.1001/jamapediatrics.2013.428.

Countdown Reason # 13: The American Stress Crisis

A new study released today by the American Psychological Association found, after studying 2000 Americans, that the day-to-day stress the average American is living with surpasses healthy stress levels.  Americans say their daily stress is at a 3.6 on a 10-point scale. Just think of that for a minute in terms of the physical “pain scale” you fill out when you go to the doctor’s.  If you are experiencing physical pain that is almost a 4 out of 10 (with a 10 being as doctors say, “the worst pain you’ve ever experienced”) that’s painful. Ditto with emotional stress. Worse, for many Americans, stress levels are on the rise — 35 percent of all Americans say their stress increased this past year, and two-thirds of U.S. adults who report living with “high stress” say their stress levels have risen. Yet 53 percent of Americans say they receive little or no support for stress management from their health care providers, and that stress management is not discussed at doctors’ visits. APA CEO Norman B. Anderson, PhD. says, “Unfortunately, our country’s health system often neglects psychological and behavioral factors that are essential to managing stress and chronic diseases. In order for our nation to get healthier, and lower the rates of chronic illnesses…we need to improve how we view and treat stress and unhealthy behaviors that are contributing to the high incidence of disease in the U.S.” When it comes to stress management and wellness, says the APA report, “there is a gap between what Americans want from their health care system and what they actually get.” I’m hoping, with all my heart, that THE LAST BEST CURE will help to fill that gap. 13 days.

Countdown Reason # 14: The Autoimmune Epidemic Was Just the First Half of the Journey

THE LAST BEST CURE will be in stores, on Amazon, Indiebound, and everywhere else in two weeks. I can hardly believe it. Many of you are fans of The Autoimmune Epidemic (now in its 5th printing!). Which, as you know, talks about all the environmental stressors and toxins we encounter in our lives that add up to inflammation and illness. I call it the barrel effect. Our bodies can handle just so much in the barrel, and then, one day, there is that one more “hit” and it spills over, leading to chronic conditions too numerous to count (well, if we are counting, 133 million adults suffer from at least one chronic condition, and the numbers are skyrocketing). I wanted you to know everything researchers know about how we can decrease what’s overfilling our barrel, both by being aware, and by knowing how to eliminate what we can. After I finished writing The Autoimmune Epidemic, I encountered a great deal of emerging research on how the chronic and acute stress we feel also acts on our immune systems exactly like a toxin. How our state of mind can overflow the barrel, or, conversely, help to protect the immune system. To our bodies, it doesn’t matter if the “hit” is viral, toxic, or stress. It looks the same. Stress and anxiety can cause our “barrel” to overflow in just the same way.  And so, I set out to research and write the “sequel” to The Autoimmune Epidemic. I’d talked about how to eliminate all the triggers we could to bring our immune system back to health, and why it was so important to do so. I felt I owed it to you to talk about the one thing in our “barrel” that is most under out control: reversing the inflammation-promoting agitation, fear, stress, pain and anxiety we all encounter and experience in our lives, which leaks, like a toxin, into our barrel. Thousands of researchers have been studying how to best use scientifically studied methods to do just that. And how to activate instead, the healing secrets of the brain. I would like to think my last two books form something of a health equation: The Autoimmune Epidemic      +      The Last Best Cure  =  Reclaim Your Body, Your Joy, Your Well-being, Your Life.

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