Every Woman Was Once a Girl: Why We Need to Talk About the Unique Biological Effects of #ToxicChildhoodStress and #FemaleAdversity on Women’s Bodies and Brains.

This is Part Two of my Three Part Series, Female Adversity: The Female Body and Brain on Toxic Stress

(CRUCIAL NOTE HERE BEFORE YOU READ: Boys’ immune systems become dysregulated in response to #toxicstress too, and that leads to disease and changes to the brain that we also need to talk about more openly AND compassionately. Today I’m focusing on girls’ unique immune response to #toxicstress.)

So, exactly what happens in a girl’s body, in response to #toxicstress, that leads girls to be more likely to be ill as adult women? EVERY WOMAN WAS ONCE A GIRL. So, we should figure this conundrum out, right?

(For more on the scientific link between toxic childhood stress, being female, and later developing autoimmune disease, depression and other conditions, please read PART I of this essay, Why Girls Who Face Toxic Stress are More Vulnerable to Adult Illness: The Shocking Relationship Between Being Female, #ACEs, Autoimmune Disease and Depression)

Well, it turns out that girls’ developing immune systems react differently to toxic stress than boy’s do. This is because of some basic physiological differences between women and men. Women are, generally, physically smaller than men and our hearts and lungs are much smaller in size. Yet our anatomy makes added room to carry a fetus in order to create new human life.

Our smaller heart, lungs, and organs still have to be able to do everything a human male does – pump oxygen, circulate blood, run fast, think fast, be awake 16 or 17 hours a day – and have the necessary fuel to carry a child to term. We have to do double duty, on half the machinery.

Women can do so much more on less because we also have higher baseline levels of the hormone estrogen. Estrogen acts as a kind of messenger, carrying information between groups of our cells. Say we are stressed, or catch a flu, or get a vaccine – estrogen helps us, as women, have a more robust immune response. This more robust immune response is also thanks to steroid hormones known as glucocorticoids (or GCs). Glucocorticoids are produced by the adrenal gland and are anti-inflammatory. They help regulate inflammation.

If a woman is pregnant, glucocorticoids help us to keep our baby safe and carry it to term, even if we come down with the flu, or have a physical injury. Our immune system is poised, all the time, to protect our ability to carry another life.

This heightened female immune response also means that when our immune system sets out to fight off any foreign invader, such as a virus or bacteria, as women we also produce more of what are called antibodies, or fighter immune cells. That’s good. BUT it can also be a problem. As women, when we produce more antibody fighter cells, we also produce more autoantibodies. Autoantibodies are rogue fighter immune cells that can mistakenly attack the body’s own tissue or organs, in what we refer to as friendly fire. As in #autoimmunedisease.

When women, ESPECIALLY GIRLS, repeatedly face #toxicstress during the developmental years, over time, their stress response begins to be dysregulated. Glucocorticoids, or GCs, become less able to properly regulate a healthy, appropriate immune response, which leads to more inflammation.

Now remember, in the face of threats that prick up the immune system (which includes infections, physical injury, AND social threats and stressors), girls ALSO make more antibodies AND more rogue autoantibodies – again, because we have so much more estrogen.

This leads to a double whammy. It’s a simple equation:

A (Glucocorticoids stop regulating a proper immune response in face of #toxicstress)

+ B (Estrogen leads to production of more autoantibodies, which can attack the body itself)

= C (When girls face toxic stress, rogue autoantibodies can run amok, promoting slow-brew inflammation, and later disease)

This means that, over time, a woman’s immune system is a lot more likely to begin to attack her own body. This accounts for the fact that #autoimmunediseases strike women at three times the rate of men. For some illnesses that ratio is far higher. Examples. Women develop Hashimoto’s thyroiditis at a rate of 10:1 compared with men. In lupus, that rate is 9:1. In Sjögren’s syndrome, 9:1. #AutoimmuneDisease is one of the top ten leading causes of death in women under the age of sixty-five.

Fifty million Americans have an autoimmune disease, and three-quarters of these are women.

Women are also twice as likely as men to have chronic pain syndromes. Women with an ACE score of 3 are significantly more likely to have chronic pain syndromes including headaches, back and neck problems. Women are also more likely to have “contested conditions” – meaning the medical profession is still debating whether these autoimmune conditions are real or just psychosomatic — such as #chroniclyme, #chronicfatigue and #fibromyalgia.

A heightened inflammatory stress response also affects the architecture of the #femalebrain differently than the male brain. A girl’s brain, on adversity, is a vulnerable brain in unique ways. For instance, both boys and girls who grow up with #toxicstress demonstrate, on brain scans, fewer neural connections between the pre-frontal cortex (the decision-making center of the brain) and the hippocampus (an area of the brain that helps us to make sense of our emotions and experiences). But, in girls who grow up with #toxicstress and #ACEs, another area of neural connectivity is affected. It goes offline. Synaptic connections between an area of the brain known as the amygdala (the fear-and-alert center of the brain) and the pre-frontal cortex are also weakened.

This means that girls who experience #ACEs are more likely to grow up in a chronic state of hypervigilance. Fight or flight. Feeling that life is an emergency. This contributes to the fact that girls and women are more likely to suffer from anxiety and depression as adults than are men. Stats bear this out. One third of men with an #ACE Score of 4 later develop depression—already a high and disturbing figure—while nearly 60 percent of women with 4 #ACEs develop chronic depression in adulthood.

That means that the risk that growing up with #toxicstress and #adversechildhoodexperiences will lead to neuroinflammatory diseases such as depression and anxiety disorders is, as with autoimmune disease, TWICE AS HIGH for women as it is for men.

Physical inflammation is increasingly linked to mental health disorders. Cutting-edge research shows us that our body and brain’s immune responses function in tandem. (I’m writing more about that in my next book, out in 2019, so stay tuned for The Angel and the Assassin: The Tiny Cell That Changed the Course of Medicine. I think it’s the most important book I’ve ever written.)

Still, it can take years, sometimes decades, for toxic childhood stress to translate into symptoms, much less visible physical disease. A young girl can face a lot of chronic #toxicstress at the age of 12. BUT it may take 30 years or longer for the inflammation unleashed by that chronic adversity to progress to disease symptoms. At that late date, the link between a stressed little girl and the ill woman she’s become is invisible to the patient – and her physician.

This plays into why so many doctors miss autoimmune disease in women. Recent studies show that the average woman sees five doctors over four-and-a-half years before receiving a proper diagnosis—and nearly half of women are labeled and dismissed as “chronic complainers” in the early stages of their illness.

This means that women who’ve faced #femaleadversity and who also face #autoimmunedisease often get dismissed TWICE. From early on in life, they know if they meet up with any type of #femaleadversity  or CHILDHOOD TRAUMA– sexual harassment, date rape, sexism, abuse, at home, school or work — if they report it their version of events, what they say may very well be dismissed. Disbelieved. Their self-reports are very likely to be distrusted. Years later, in a doctor’s office, when they report their PHYSICAL #auatoimmune or #chronicpain symptoms, they get dismissed or disbelieved all over again.

The past repeats itself.

(Later this week, I’ll be adding more to this thread, in PART THREE.)

If this topic interests you personally, because it speaks to your experience, or because you work with, teach, mentor, or are parenting girls, or if you work in #ACEAwareness or #trauma prevention, sign up for my blog and newsletter now. If you haven’t yet signed up for my mailing list and/or my blog, you might want to now.

(To sign up for my mailing list and newsletter, click on the link below, and see the “Mailing List” subscription box to your right. To sign up for my blog, scroll down on the right hand side of my website’s blog page to “Never Miss a Blog Post and sign up there.)

You can also find me on Facebook or @DonnaJackNak on Twitter.

 

 

 

 

 

Why Girls Who Face Toxic Stress are More Vulnerable to Adult Illness: The Shocking Relationship Between Being Female, #ACEs, Autoimmune Disease and Depression

Hi All,

This blog is about WHY Adverse Childhood Experiences are a #METOO ISSUE. I want to talk about how and why toxic childhood stress – also as #ACEs — is a #metoo issue of the greatest magnitude. For girls and for the adult women they become.

One thing readers know about the work I do and the books I write, including Childhood Disrupted, The Autoimmune Epidemic, and The Last Best Cure, is that I focus on the intersection of neuroscience, immunology and emotion – while shining a spotlight on WOMEN’s experiences.

Connecting these dots is always an underlying theme in my work. Women, girls, toxic stress, the female brain and immune system, autoimmune disease and chronic physical and mental illness — if you care about any of these, keep an eye out for my upcoming three-part blog series in which I delve into the scientific links between them all.

Today I’m posting the first part of my three-part exploration on Growing Up With Female Adversity: The Female Body and Brain on Toxic Stress.

(For those of you who read this introduction to my three-part series in my heads-up post yesterday, skip down below to PART ONE…)

I’ve written this blog, and am offering it up freely, because I think it’s crucial that we address the unique way in which the female brain and immune system respond to environmental influences, including #ACEs, and how, in turn, this unique female brain-immune response contributes to girls being several times more likely to later develop autoimmune diseases, depression, anxiety disorders, and so many other chronic illnesses.

I’m going to break down for you, in a way no one else has, or will, how and WHY Adverse Childhood Experiences and toxic childhood stress are a #metoo issue of the greatest magnitude. For girls and for the adult women they become.

In it, I’m offering up the term — and hashtag — #FemaleAdversity — to refer to the chronic societal stress girls face growing up. Girls not only come of age with higher rates of #AdverseChildhoodExperiences, including verbal, emotional, sexual and physical abuse, girls also have to find their way to a healthy adulthood and sense of self amidst cripplingly narrow societal expectations regarding what constitutes acceptable female beauty and behavior.

All this is intensified, 24/7, by imagery of effortless female perfection on social media and in media in general. Meanwhile, girls are witnessing the sexual harassment and sexism so many adult women endure. Over time, this #FemaleAdversity can take a toll on girls’ and women’s immune systems, bodies, and brains in unique ways.

The timing for this discussion seems apt, as today we come to the end of #autoimmunediseaseawareness month as well as #womenshistorymonth and enter #childabuseprevention month. A fitting moment to delve into all of these issues.

So, Today, I’m sharing:

PART ONE: Why Girls Who Face #ToxicStress are More Vulnerable to Adult Illness: The Shocking Relationship Between Being Female, #ACEs, #AutoimmuneDisease and #Depression.

To get personal for a moment, the reason I focus so strongly, as a science journalist, on this intersection between neuroscience, immunology, emotion, toxic stress, and being female is, in part, due to my own autoimmune history. I’ve struggled most of my adult life with the lingering physical effects of having been paralyzed twice with Guillain Barre Syndrome. I’ve had a pacemaker since I was 28. I’ve struggled with peripheral neuropathy, chronic neuromuscular pain, thyroiditis, leukopenia and other medical issues throughout my adult life.

But I’m hardly alone in all this; so many of you, my readers, have faced similar and often much more difficult health issues than I have. My own experience is merely what lead me, as a career science journalist, to investigate the intersection of neuroscience, immunology and the deepest inner workings of the human heart.

What KEEPS ME GOING is the way I’ve been moved, time and again, by the hundreds of thousands of female readers who’ve shared with me their struggles, in the face of #trauma, #autoimmunedisease, #chronic illness, #depression.Wanting to help ease that suffering propels ME to uncover new understanding, new answers and insights that can change lives.

The reason I shine an up-close light on how women’s bodies, brains and immune systems are impacted in unique ways by toxic stress and emotion, and other environmental triggers, is because the science in this area is exciting and also under-reported. And the reason this science is under-reported is because it can be complex and hard to unpack in a media era that all too often relies on simplistic, broad-brush headline-centric, click-bait reporting.

If you follow my work you already know that research shows that #ACEs, such as being chronically put down or humiliated, living with a depressed, mentally ill, or alcoholic parent, losing a parent to divorce or death, being emotionally neglected, physically or sexually abused, as well as many other types of toxic childhood stressors, are linked to a much greater likelihood of developing autoimmune disease, heart disease and cancer in adulthood. Having experienced 6 categories of childhood adversity can take 20 years off your lifespan.

That’s because toxic stress changes the way our immune system responds to stressors in the future. When kids and teens experience chronic adversity, inflammatory chemicals begin to flood a child’s body and brain, plunging the body into a state of chronic hypervigilance.

Our genes are ALWAYS in a back and forth dance with our environment. If you’re a child growing up in an environment that is chronically stressful, and don’t have reliable adults to turn to, that meets the definition of toxic stress.

Toxic childhood stress begins to cause changes in the architecture of the developing brain, and it engenders profound epigenetic changes in the genes that oversee the stress response. In fact, Yale researchers recently found that children who’d faced Chronic Unpredictable Toxic Stress (what I term C.U.T.S.) demonstrate changes “across the genome” in genes that oversee the stress response. These changes re-set the stress response to “high” for life.

They also showed changes in genes that play a role in developing autoimmune disease, cancer, depression, anxiety and so on.This correlation is particularly stark for WOMEN. For each category of #ACEs a girl faces, her chance of developing a serious autoimmune disease in adulthood increases by 20 percent. For instance, a girl who faces three categories of Adverse Childhood Experiences has a 60 percent greater chance of developing an autoimmune disease so serious she requires hospitalization as an adult woman, as compared to a girl who grows up without #toxicstress.

For every category of #ACEs a man has faced, his chances of being hospitalized with an autoimmune disease increases by about 10 percent – still a significant and disturbing correlation and one we also need to pay attention to.

We also know that girls face more #ACEs growing up in general. In fact, girls are 50% more likely to have experienced 5 or more categories of childhood adversity. These include sexual and physical abuse, emotional or physical neglect, growing up being chronically humiliated, or growing up with a parent with a drug/alcohol problem or mental illness, or losing a parent to divorce/death.

These higher rates of #ACEs for girls mostly revolve around the fact that girls are physically smaller than men and have less societal power or equality in family life – and are more vulnerable to, and likely to be victims of, physical, sexual and emotional abuse, and harassment.

Just think of today’s #METOO movement. It’s all about systemic emotional, sexual, physical harassment and humiliation and abuse based on being in a situation in which men in the culture (and “culture” can include members of your family of origin) are more powerful than you.

We also know that girls who experience 2 or more categories of #ChildhoodAdversity are twice as likely as boys who experience 2 or more types of childhood adversity to develop autoimmune disease in adulthood.

In fact, the relationship between being female, facing adversity as a teenager or child, and later developing an #autoimmunedisease, is so strong it resembles the link between smoking and cancer, or drunk driving and having a car accident.

Again, the more childhood adversity a girl grows up with, the higher her risk becomes for adult disease, and the more likely she is to end up in the hospital at some point in her adult life in order to be treated for a serious autoimmune condition. As a science journo when I saw these statistics I wanted to know: WHY are women who experience childhood adversity twice as likely to suffer from disease as adults, compared to men?

What happens in a girl’s body, in response to #toxicstress, that leads girls to be more likely to be ill as adult women? EVERY WOMAN WAS ONCE A GIRL. So, we should figure this conundrum out, right?

Tomorrow, I’ll try to do just that for you, in Part Two: Every Woman Was Once a Girl: Why We Need to Talk About the Biological Effects of #FemaleAdversity on Women’s Bodies and Brains

If this topic interests you personally, because it speaks to your experience, or because you work with, teach, mentor, or are parenting girls, or if you work in #ACEAwareness or #trauma prevention, sign up for my blog and newsletter now. If you haven’t yet signed up for my mailing list and/or my blog, you might want to now.

(To sign up for my mailing list and newsletter, click on the link below, and see the “Mailing List” subscription box to your right. To sign up for my blog, scroll down on the right hand side of my website’s blog page to “Never Miss a Blog Post and sign up there.)

You can also find me on Facebook or @DonnaJackNak on Twitter.

Female Adversity: The Female Body and Brain on Toxic Stress

Hi All,

Three things I wanted to let you know about: later this weekend I’ll be posting a three part essay about women, toxic stress, and the female immune system — and why this topic matters now more than ever (more on that below!); an update on my next book, The Angel and the Assassin; and upcoming speaking events!

One thing readers know about the work I do and the books I write, including Childhood Disrupted, The Autoimmune Epidemic, and The Last Best Cure, is that I focus on the intersection of neuroscience, immunology and emotion – while shining a spotlight on WOMEN’s experiences. Connecting these dots is always an underlying theme in my work. Women, girls, toxic stress, the female brain and immune system, autoimmune disease and chronic physical and mental illness — if you care about any of these, keep an eye out for my upcoming three-part blog series in which I delve into the scientific links between them all.

I’ve written this upcoming blog, and am offering it up freely, because I think it’s crucial that we address the unique way in which the female brain and immune system respond to environmental influences, including #ACEs, and how, in turn, this unique female brain-immune response contributes to girls being several times more likely to later develop autoimmune diseases, depression, anxiety disorders, and so many other chronic illnesses.

I’m going to break down for you, in a way no one else has, or will, how and WHY Adverse Childhood Experiences and toxic childhood stress are a #metoo issue of the greatest magnitude. For girls and for the adult women they become.

If you haven’t yet signed up for my mailing list and/or my blog, you might want to now. (To sign up for my mailing list and newsletter, see the “Mailing List” subscription box to your right. To sign up for my blog, scroll down on the right hand side of this page to “Never Miss a Blog Post and sign up!)

I’m calling this three-part exploration:

Growing Up With Female Adversity: The Female Body and Brain on Toxic Stress. In it, I’m offering up the term — and hashtag — #FemaleAdversity — to refer to the chronic societal stress girls face growing up. Girls not only come of age with higher rates of #AdverseChildhoodExperiences, including verbal, emotional, sexual and physical abuse, girls also have to find their way to a healthy adulthood and sense of self amidst cripplingly narrow societal expectations regarding what is acceptable female beauty and behavior. All this is intensified, 24/7, by images of effortless female perfection on social media and in media in general. Meanwhile, girls are witnessing the sexual harassment and sexism so many adult women endure. Over time, this #FemaleAdversity can take a toll on girls’ and women’s immune systems, bodies, and brains in unique ways.

So, in this series I’ll be delving into:

Part One: Why Girls Who Face #ToxicStress are More Vulnerable to Adult Illness: The Shocking Relationship Between Being Female, #ACEs, #AutoimmuneDisease and #Depression.

Part Two: Every Woman Was Once a Girl: Why We Need to Talk About the Biological Effects of #FemaleAdversity on Women’s Bodies and Brains.

Part Three: #FemaleAdversity is a Unique Form of #ToxicStress — One We Haven’t Been Paying Enough Attention To — And We’d Better Start Soon.

If this topic interests you personally, because it speaks to your experience, or because you work with, teach, mentor, or are parenting girls, or if you work in #ACEAwareness or #trauma prevention, sign up for my blog and newsletter now.

2. Here, too, is a very brief update about my next book THE ANGEL AND THE ASSASSIN: The Tiny Cell That Changed the Course of Medicine, and Gives us a Radically New Way of Looking at Human Well-Being, which will be out with Ballantine Books (Random House) in Fall 2019. I’m writing as fast as I can! And what I’m researching and reporting on is as promising for human health as it is mind-blowing. I’m happy to say, I’ve already turned in the first 200 pages.

In THE ANGEL AND THE ASSASSIN, I’m on a mission to de-stigmatize brain-related health challenges, and to show how chronic conditions like depression, anxiety, learning disabilities, mood disorders, memory issues, and Alzheimer’s all involve one tiny, overlooked (and all too often, overactive) brain immune cell called microglia, which functions as the “white blood cell of the brain.” These tiny glial cells are in constant dialogue with the body’s immune system, and can be all too easily triggered by physical or emotional trauma, toxic stress, environmental toxins, infections, and inflammation in the body itself. All of these can, in turn, cause microglia to become agitated and destroy brain synapses and circuitry, generating neuroinflammation — in much the same way that rogue immune cells in the body can generate a slow brew inflammatory process that leads to the body attacking itself, as in autoimmune disease.

This truly amazing discovery – and the new understanding that the brain is an immune organ, ruled by these little reactive immune cells called glia — is one of the most revolutionary discoveries in the history of science, and it’s changing everything, including leading to exciting new avenues for treating seemingly intractable life-altering disorders.

Once again, in  The Angel and the Assassin, as in all my books, I’ll be examining what this means specifically for women and girls, who suffer disproportionately from trauma, toxic stress, autoimmune disease, depression, and so many chronic illnesses. Stay tuned!

3. Finally, for those who are interested in knowing about my upcoming events, here are a few of the venues where I’ll be lecturing over the next few months. Both of these events offer CME and CPE Credits for professionals who want to be trauma-informed, learn about ACEs Science, and the latest science on resiliency.

Keynote, Rutgers University DIS[RU]PT TRAUMA Conference, Thursday, May 31st, 9 a.m. – 12:00. I’ll also be offering a break out workshop.

Golisano Children’s Hospital 16th Annual Pediatric Conference, Saturday June 9th, 1:30, at the Sanibel Harbour Marriott Resort & Spa.

Hope to see you at one of these events!

You can also find me on Facebook or @DonnaJackNak on Twitter.

Donna

Hope You’ll Come Say Hi at One of My Upcoming Talks

Hi Friends:

First I want to say a heartfelt thank you to the hundreds of women who reached out to me, offering to be interviewed for my next book, THE ANGEL AND THE ASSASSIN: The Tiny Cell That Changed the Course of Medicine, and Gives us a Radically New Way of Looking at Human Well-Being, which will be published by Ballantine Books (Random House) in 2019. Your emails and stories, moved me. I’m on a mission to de-stigmatize brain-related health challenges, and you’ve once again proven you’re the best readers on the planet. (I do have all the interviewees I need at this point, and thank you all for offering to help. You’re amazing.)

I hope the book, when it comes out, helps every one of you. I’m setting out to show — based on hundreds of hours of interviews with neuroscientists and thousands of research papers — how and why symptoms of depression, anxiety, learning disabilities, OCD, memory issues, and Alzheimer’s are unequivocally related to tiny, overlooked (and all too often, overactive) brain immune cells – called microglia – which function as the “white blood cells of the brain.” When these little cells get agitated by triggers like toxins, infections, stressors, physical or emotional trauma, they can destroy brain synapses and circuitry, causing “neuroinflammation” and “neurodegeneration,” the same way that your white blood cells cause inflammation in your body. This truly amazing discovery – and the new understanding that the brain is an immune organ, ruled by these little immune cells — is one of the most revolutionary discoveries in the history of science, and it’s changing everything, including leading to exciting new avenues for treating seemingly intractable life-altering disorders.

To report this book, I’ve been traveling all over the country. What I’m finding is pretty much blowing my mind. (For updates, sign up for my blog and newsletter (scroll down on the right hand column of this page!)

Meanwhile, I’ll be giving several exciting lectures this fall and I hope some of you will be able to come say hi. (Psst… if you’re a UK reader, I’ll be in London soon to deliver the keynote for an international conference on chronic pain, held by the amazing group, SIRPA, at the Royal Society of Medicine (details below). Please join us and say hi!)

Here are a few of the upcoming venues where I’ll be giving keynotes and doing booksignings:

October 2-3, 2017
Keynote Speaker, Booksigning and Workshop, Children’s Trust of South Carolina
2017 Prevention Conference: Embracing Prevention, Empowering Communities
Columbia Metropolitan Convention Center
1101 Lincoln Street, Columbia, S.C.
Register here.

October 15, 2017
Keynote Speaker, SIRPA Chronic Pain Conference
Chronic Pain: The Role of Emotions
Royal Society of Medicine
London, England
Award-winning science journalist Donna Jackson Nakazawa who will discuss the decades of research linking adverse childhood experiences to ill-health, including chronic pain, in later life.
To learn more about the role of Adverse Childhood Experiences and emotions in chronic pain, register here.

October 19th, 2017
Keynote Speaker
Stony Brook Children’s Hospital School Intervention Program,
Helping Children with Chronic Illnesses Thrive
I’ll be talking about Childhood Disrupted: How Your Biography Becomes Your Biology – and how we can help kids facing chronic conditions and medical adversity achieve resiliency and well-being.
Stony Brook, New York
Register here.

 

November 14th, 2017
1 p.m. EST, I’ll be giving a live interactive chat & talk on
Survival of the Nurtured: Well-Being, Self-Care, and ACEs, as part of ACEs Connection 2017 Parenting With ACEs Fall Chat Series
(Members of ACEs Connection can Join Parenting with ACEs Community & go there at time/day of chat. If you’re not a Member of ACEs Connection, you can become a Member (free). Join ACEs Connection a day or more before chat. Then, join the Parenting with ACEs Community (PWA) & go there at time/day of chat. See “featured chat” at top of PWA page.) Be sure to check out the other speakers, too — the amazing Sebern Fisher, and Belleruth Naparstek.)

Also, I thought I’d share this essay one more time; it recently went viral with over 2 million hits worldwide. If it resonates with you, feel free to share on social media. It’s about the importance of the medical profession becoming trauma-informed to better help patients: Childhood Trauma Leads to Lifelong Chronic Illness – So Why isn’t the Medical Community Helping Patients?

Hope to see you at one of the above events. And you can always find me on Facebook or Twitter.

Here’s to your healing,

Donna

Want to Be Part of My Next Book Project?

Hello friends:

For my next book, I’m interviewing women and young adults experiencing mood, anxiety and/or learning/cognitive issues, who are curious about the concept that brain based symptoms have neurobiological, immunological, physical roots. If you are, or know, a woman in mid-life, for whom this resonates, and are in an extended family that faces depression, anxiety, mood and learning/cognitive issues, and would like to share your experiences and possibly have me report on your journey of discovery, please message me (or have them message me) by commenting below, or, contact me privately, here. If you have a family history of mental health and autoimmune disorders, this is also relevant. Interviewees can absolutely be disguised.

This is what my attic office looks like as I map out the chapters for my next book, THE ANGEL AND THE ASSASSIN: The Tiny Cell That Changed the Course of Medicine — and Gives us a Radically New Way of Looking at Human Well-Being. I LOVE writing this book. The science is so exciting, and I think it will help so many readers. (Pssst… can you spot my writing companion in this photo?)

In this book, called THE ANGEL AND THE ASSASSIN: The Tiny Cell That Changed the Course of Medicine, and Gives us a Radically New Way of Looking at Human Well-Being, which will be published by Ballantine Books (a division of Random House) in 2019, I’m looking at groundbreaking, recent scientific discoveries at top labs around the country showing unequivocally that symptoms of depression, anxiety, learning disabilities, OCD, memory issues, and Alzheimer’s emerge because of overactive brain immune cells – called microglia – which function as the “white blood cells of the brain.” In the face of 21st Century triggers — from stress to toxins – these little cells get agitated and destroy neurons and synapses, causing “neuroinflammation” and “neurodegeneration,” the same way that your white blood cells cause inflammation in your body. This discovery – and the new understanding that the brain is an immune organ, ruled by immune cells (just like all the other organs in the human body) is one of the most exciting and important discoveries in the history of science, and is leading to exciting new avenues for treating seemingly intractable life-altering disorders.

The fact that our brain is an immune organ and is affected by our immune health on a cellular level is not often addressed, yet this fact can have a profound effect on how individuals view their suffering, and the treatment they seek.

My goal is to de-stigmatize these diseases by taking you into cutting edge labs where neuroscientists are showing that brain based disorders are due to physical changes that lead to disease symptoms – and show what we can do to heal. Thanks!!

If this whole idea captures your imagination, and you and or your family are affected by these disorders – let me know!!!

This year’s Learning & The Brain Conference

In other recent news, I so enjoyed lecturing at this year’s Learning & The Brain Conference, in Arlington, Virginia. (Learning & The Brain teams up with Harvard, Yale, MIT, Stanford, UC Berkeley, University of Chicago, Johns Hopkins, and other leading institutes to provide the latest findings on brain health and brain resiliency). I loved talking to an amazing group of educators about Childhood Disrupted: How Your Biography Becomes Your Biology – and how important mentors, adults and teachers are in helping kids achieve resiliency and well-being.

In my fall lecture series I’ll be speaking at venues including the amazing SIRPA international conference on chronic pain in London in October 2017;  Stonybrook Children’s Hospital, in Stonybrook, New York; and the South Carolina Children’s Trust, among other venues.

Don’t forget — reach out if my newest book resonates with you — I’d really love to talk to you! Comment below, or, if you prefer, contact me privately. Or, ping me on Facebook!

Thanks so much!

Donna

P.S. In case it’s helpful, fyi, I’m told that this weekend Childhood Disrupted is at its all time lowest price on Amazon — under $10.

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How to Win The Doctor Lottery

Hi All, and Happy Spring!

Doctor Patient photoI’m proud to share this very personal essay I wrote for the April 2017 issue of the journal, Health Affairs, “How to Win The Doctor Lottery: Not every doctor-patient encounter is healing, and it can seem a game of chance. One patient explores what it takes to win.” Or, if you prefer, you can hear me read this essay aloud in this audio recording on the Health Affairs podcast!

If you’re looking for support for your own healing journey, I hope you’ll enjoy my recent article on ACEsTooHigh, about the importance of the medical profession becoming trauma-informed, Childhood Trauma Leads to Lifelong Chronic Illness – So Why isn’t the Medical Community Helping Patients?

Let me know if these resonate with you.

For those in the Washington, D.C. and Northern Virginia area, I’ll be speaking this Saturday at the annual Learning & the Brain Conference. Hope to see you there.

Last, but not least, stay tuned — I’ll be announcing my next book very, very soon. I hope, when I do, you’ll be as excited about it as I am!

To your wellness!

Donna

How Adverse Childhood Experiences Affect Adult Illness

A screenshot of my Q. and A. -- to watch it, click on this link: https://www.youtube.com/watch?v=pcZ_uLIB7V8

A screenshot of my Q. and A. — to watch click this link: https://www.youtube.com/watch?v=pcZ_uLIB7V8

Hi All,

Here is a recent video interview, in which I share my thoughts on How Adverse Childhood Experiences Affect Adult Illness, why our new understanding of this science must change the way we do medicine, and why I wrote my book, Childhood Disrupted. Produced by Studio4.

Hope you’ll enjoy!

Donna

Come Join Me For Talks & Booksignings in July 2015 on Childhood Disrupted: How Your Biography Becomes Your Biology, and How You Can Heal!

DSC_0090-1Hope you can come join me on Tuesday July 7th at 7:00 at Baltimore’s lovely Ivy Bookshop for a talk, chat, and booksigning!
Tuesday, July 7th, 2015
7:00 p.m.
Childhood Disrupted: How Your Biography Becomes Your Biology, and How You Can Heal — a Discussion & Book Signing
with Donna Jackson Nakazawa
http://www.theivybookshop.com/

Or, come join me on Friday, July 17th at the Annapolis Bookstore for a talk, chat, and booksigning!
Friday, July 17, 2015
7:00 p.m.
Childhood Disrupted: How Your Biography Becomes Your Biology, and How You Can Heal — a Discussion & Book Signing
with Donna Jackson Nakazawa

http://annapolisbookstore.com/

Hope to see you at one of these!

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My Next Book! Childhood Disrupted: How Your Biography Becomes Your Biology, and How You Can Heal

What my desk looks like as I begin editorial revisions for my next book: Childhood Interrupted: How Your Biography Becomes Your Biology

Every once in a while, as a writer, I sort of “disappear” — taking a break from blogging and social media to fully immerse myself in finishing a new book. I’m happy to say, in 2015, you’ll be able to see what I’ve been so busy working on (and why I’ve been so quiet)!

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A Q. and A. with “Between the Covers” on What Compelled me to Write The Last Best Cure

I recently spoke with Melanie Brevis, blogger at Baltimore County Public Library System, and we had a great chat!

Between the Covers with Donna Jackson Nakazawa

Donna Jackson NakazawaBaltimore author Donna Jackson Nakazawa discusses her latest book, The Last Best Cure, on Wednesday, April 16 at 7 p.m. at the Perry Hall Branch, sponsored by the Friends of the Perry Hall Library. The award-winning science journalist and writer recently answered questions for Between the Covers about her book.

Before The Last Best Cure, you authored another book about autoimmune diseases, The Autoimmune Epidemic. What insights or new knowledge did you gain between that book and The Last Best Cure? What was going on in your life prior to writing these books?

The Autoimmune Epidemic focused on how modern chemicals in the world around us and in our diet are overwhelming the human immune system, contributing to rising disease rates and chronic illnesses. The Last Best Cure takes this research a step further and investigates “psychoneuroimmunology,” a new field of study that investigates how mind states, such as anxiety, fear, worry, rumination, anger and pain, can end up damaging our immune function in much the same way as environmental chemicals. Prior to this, I was struggling with my own health crises. The Last Best Cure is my chronicle of a one-year doctor/patient experiment to see if altering my mood state might shift my inflammatory markers and perhaps even improve my physical well-being.

 The Last Best Cure has received much critical praise, described as a book that will offer hope for recovery, and change and save lives. What is the most important insight or piece of information you want readers to take away from your book?

I want people to know that there already exists an understanding as to how we can activate the healing potential of the brain. Understanding how to do this gives us powerful tools, ways to change the messages our brain is sending to our cells and our body. Everyone deserves to live the life they want, and these tools can help us all achieve a greater sense of well-being, and even joy.

You were already an award-winning science journalist and writer when you began writing these last two books. What was it like writing professionally about a topic that was also very personal to you? Were there any “aha” moments for your own life as you were writing?

At first, I was only going to write about my personal experiences in the introduction to The Last Best Cure, but my editor thought readers would want to read more about how I also went on this transformational journey myself. She thought it would help convey to readers that we can all take this journey, no matter what physical or emotional health challenges we face. There was so much that I realized along the way about adversity, self-respect and how they play a role in adult illness. Now I’m profoundly grateful to have taken this journey: Life is sweeter, relationships are better and it’s a better, more meaningful way to live.

In addition to being about healing and recovering personal joy, The Last Best Cure is a story about a health epidemic. What steps do we need to take now to secure a better health outlook for future generations?

We need to absolutely, completely and radically change how we view the doctor/patient relationship. If we keep up the current “medical factory” model we’re going to see very little progress in managing chronic health issues. Right now, 133 million adults in America have chronic illnesses, not counting the 22 million with addiction – and these numbers are rapidly climbing. The tools to help patients participate in their own healing and facilitate greater well-being exist; it just requires that physicians incorporate new practices into their doctor/patient paradigm. In order to do this, we must change the way we as a society view treatment, health care and the doctor/patient relationship.

Are there any new books in the works?

Yes, one due out at the end of next year called Childhood Interrupted: How Adversity in the Past Writes the Story of Our Future – And How We Can Change the Script (Atria/Simon & Schuster). It’s a deeper, more extended study of how childhood adversity can create changes in the brain and in our immunology that impact our health long into adulthood – and what we can do to reverse those effects as adults. I’m telling cutting-edge stories of science, about how even very common forms of childhood adversity can reset our immune system to be more stress-reactive, sparking a state of chronic low-grade neuroinflammation for life. I want to help readers understand how the stress we meet in childhood can determine our lifelong “set point” for emotional reactivity, inflammation, disease and depression – and what we can do to reverse the impact of early adversity and trauma years later, in adulthood, to regain our physical and emotional well-being.

How long has the Baltimore area been home to you? What do you like best about living in this area?

My family moved to Baltimore four years ago from Annapolis; my mom and my husband’s parents were already living here, so it just made sense. What I like best about Baltimore is its people. Baltimoreans are real, genuine, honest, intellectual, creative, smart and energetic. They’re committed to their community and engaged in making this a better place to live. We love it here. It’s a vibrant place to be.